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ICON and Genomics England

Published on Apr 25, 2016 The 100,000 Genomes Project is creating the world’s largest genome sequencing project for cancers and rare diseases, and has the potential to transform the diagnosis and treatment of cancers and rare diseases. As Data Management Partner for this transformative project, ICON is using its world-class capabilities to validate and securely manage the large, complex data …

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Drawn to Science: T-cell bispecific antibodies

Published on May 31, 2016 At Roche Pharma Research and Early Development, we are working on a novel form of engineered antibodies for cancer immunotherapy that we call T-cell bispecific antibodies. We consider them match-makers between T-Cells and cancer cells. With two handles, they recognize specific markers on the surface of cancer cells. A third handle is designed to hook …

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Chasing Metastatic Cancer Cells

Link via Winship Cancer Institute of Emory University Understanding cancer cell behavior is a fundamental step toward advancing precision medicine. Winship’s Adam Marcus, PhD, shows how his lab is isolating and studying the behavior “leader” cells that may be the key to cancer metastasis.

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White House and President Obama Hosts a Precision Medicine Initiative Summit

On the one year anniversary of the launch of the Precision Medicine Initiative, President Obama participates in a panel discussion moderated by Dr. James Hamblin of The Atlantic on the importance of PMI in South Court Auditorium at the White House, February 25, 2016. “Doctors have always recognized that every patient is unique, and doctors have always tried to tailor …

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What is Precision Medicine?

Precision medicine aims to collect, connect, and apply vast amounts of data and information about our health to help guide more precise and predictive medicine worldwide. Learn more at http://precisionmedicine.ucsf.edu/

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Liquid Biopsy Promotes Precision Medicine By Tracking Patient’s Cancer

Published on Nov 4, 2015 In a study published in Nature Communications, Dr. Muhammed Murtaza, who holds a joint appointment at Mayo Clinic and Translational Genomics Research Institute (TGEN), and colleagues, describe an extensive comparison between biopsy results and analysis of ctDNA in a patient with breast cancer. In the following video, Dr. Murtaza describes how circulating tumor DNA in …

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CRISPR: A DNA Word Processor for Editing the Genome

Since the discovery of DNA’s fundamental role in building and sustaining life, scientists have dreamed of having the ability to easily edit DNA in very precise ways. This video explores how a group of scientists made a major breakthrough in understanding the bacterial immune response, called the CRISPR/Cas system, and discovered a way to utilize this system to create a …