Programme 2020
Epigenetics and Epigenomics in Health and Disease
10-11 September 2020, Brussels

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For any enquiries about speaking opportunities please email Steve Coldicott
DAY 1 - Thursday September 10, 2020
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09:00 - 17:15
Conference Registration
09:00
Welcome and Opening Remarks
09:15
Session One

1

Epigenetic Mechanisms and Diseases
Intro to follow...

 Chair: Danette Daniels

Panellists:

A. Epigenetic Pathways as Targets in Human Cancer

  Shelley Berger, Philadelphia, USA

B. Epigenetic control of neurodegeneration

 Anne Schaefer, NY, USA

C. Unveiling polycomb functions in stem cells and cancer

 Luciano Di Croce, CRG, Barcelona, Spain

D. Role of integrators in human pahtologies

  Ramin Shiekkathar, Miami, USA

E. Principles of Epigenetics and Chromatin in Development and Human Disease

 Ali Shilatiffard, Chicago, USA

12:30
Lunch & Posters
13:45
Company Presentations
14:00
Session Two

2

Chromatin Dysregulations in Human Disorders
Intro to follow...

  Chair: Richard Gregory

A. Epigenetics: One Genome, Multiple Phenotypes

 Danny Reinberg, NYU, USA

B. tRNA-derived small RNAs support genome stability during epigenetic reprogramming

 Andrea Schorn, Cold Spring, USA

C. BAF Complex Structure and Function in Human diseases

Cigal Kadosh, Harvard, USA

D. Epigenetics as a Gatekeeper to DNA Amplification

 John Westhine, Harvard, USA

E. Drawing on proteins disorder: how viruses impact chromatin function

Sasha Tarakhovsky, NY, USA

17:30
Session Ends
DAY 2 - Friday September 11, 2020
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09:00 - 12:00
Conference Registration
09:00
Session Three

3

Session 3: The RNA world : non-coding RNA and RNA epigenetics
Intro to follow...

Chair: John Westhine, Harvard, USA

A. Replication-Coupled Silencing and Spreading with RNAi

Rob Martienssen, Cold Spring, USA

B. Modifications of RNA: Their Function and Role in Cancer

Tony Kouzarides, Cambridge, UK

C. Gene Expression Regulation by RNA Methylation

Yungui Yang, CAS, Beijing, China

D. Oncogenic role of the METTL1/WDR4 RNA methyltransferase complex

  Richard Gregory, Boston Children’s Hospital, USA

E. Targeting RNA modifications in cancer

  Michaela Frye, German Cancer Research Centre, Heidelberg, Germany

12:15
Lunch and Posters
13:15
Company Presentations
13:30
Session Four

4

Novel Therapeutic Discoveries in Epigenetics
Intro to follow...

 Chair: Luciano Di Croce

A. Molecular Mechanisms Governing Sensitivity and Resistance to Epigenetic Therapies

  Mark Dawson, Melbourne, AUS

B. Epigenetic Targets for the Treatment of Human Diseases

  Rab Prinjah, GSK, UK

C. Role of Polycomb in human diseases

  Kristian Helin, NY, USA

D. Identification of novel epigenetic therapeutic targets

  Yang Shi, Harvard, USA

E. Understanding the Functional Pathway of BET Family Degradation Compounds

  Danette Daniels, Promega, USA

17:30 - 19:30
Free Time
20:30
Conference Event
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